Which pharmacogenetic tests are used in the treatment of colon cancer?

Date:2023-01-07
1. KRAS testing - to evaluate for mutation in the KRAS gene, which is associated with an increased risk for developing colon cancer. 2. BRAF testing - to identify the mutation in the BRAF gene, which is associated with an increased risk for developing colon cancer as well. 3. UGT1A9 genotyping - to assess potential metabolic differences in a medication commonly used to treat colon cancer 4. Cytochrome P450 2C9 (CYP2C9) genotyping - used to assess potential metabolic differences in certain medications that are commonly used to treat colon cancer. 5. MTHFR genotyping - used to assess variations in the methylenetetrahydrofolate reductase (MTHFR) enzyme, which is involved in the metabolism of certain medications used to treat colon cancer.
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