Can liposomes be used for mass spectrometric analysis of membrane proteins?

Date:2023-01-06
Yes, liposomes can be used for mass spectrometric analysis of membrane proteins. The analysis involves attaching a membrane-impermeable molecule, such as a lipid, to the membrane protein, allowing the protein to be extracted from the membrane. The molecule can then be broken down by mass spectrometry, allowing for the characterisation of the protein. Liposomes can be used to carry out the extraction in an efficient manner, as they can provide a well-controlled environment for the process.
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